CEA (CEA31)

Anti-CEA is employed as a tool to assist in the distinction between adenocarcinoma and mesotheliomas, along with other markers such as calretinin, CK 5/6, D2-40, HBME-1, Napsin A, MOC-31, and Ber-EP4. Another suggested use of anti-CEA is to immunophenotype various metastatic adenocarcinomas as a means of identifying their origin. Anti-CEA positivity is seen in adenocarcinomas from the lung, colon, stomach, esophagus, pancreas, gallbadder, urachus, salivary gland, ovary, and endocervix.1-8