Renal Cell Carcinoma (PN-15)

Anti-renal cell carcinoma (RCC) recognizes a 200 kD glycoprotein localized in the brush border of the proximal renal tubule. This antibody immunoreacts with approximately 90% of primary renal cell carcinomas and approximately 85% of metastatic renal cell carcinomas. Other tumors that may react with this antibody are parathyroid adenoma and an occasional breast carcinoma.1 Nephroblastoma, oncocytoma,2 mesoblasticnephroma, transitional cell carcinoma, and angiomyolipoma are not labeled with this antibody.1-3